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Obese people without metabolic risk factors for diabetes and heart disease are not at high heart diseases typical of obesity, according to a long-term Dutch study. It was however revealed by the study that only a small percentage of the obese population represents this “safe” community.
Study co-author Andre van Beek, of University Medical Center Groningen, Groningen, the Netherlands, said some individuals who are obese have a normal cardiovascular risk profile and are not an increased risk for heart and blood vessel diseases.
From in.news.yahoo.com:
The study found that in a large population of obese individuals, only 6.8 percent were “metabolically healthy,” meaning they had no history of heart disease or stroke, no diabetes or high blood pressure, and no dyslipidemia (irregularities in blood fats, including cholesterol and triglycerides) or any use of cholesterol-lowering medications.
To conduct the research, the authors identified 1,325 obese individuals from 8,356 subjects participating in the Dutch PREVEND (Prevention of Renal and Vascular Endstage Disease) study, who ranged in age from 28 to 75 years. Only 90 obese subjects were metabolically healthy.
Over 71/2 years, cardiovascular disease developed in just one of these 90 individuals. This percentage (1.1 percent) was not significantly higher than that in metabolically healthy subjects who were overweight (1.3 percent) or of normal weight (0.6 percent), the researchers reported.
These results indicate that metabolically healthy obese individuals appear to have protection against cardiovascular disease, van Beek said.
However, he added, “They are a small subset of the total obese population. And they may still suffer from other obesity-associated diseases like muscle and joint complaints.”
The results were presented at The Endocrine Society’s 92nd Annual Meeting in San Diego.
